SIF 2nd Cohort Fellows - Maria Herrero Herrero, CY Cergy Paris Université

Curriculum Vitae

  • Education
2022, PhD in Health and Wellness Technologies, Polytechnical University of Valencia (Spain), Biomaterials

2022, Master’s Degree in Secondary Education, University of Valencia (Spain), Education

2021, University Expert in e-Learning, Polytechnical University of Valencia (Spain), Education

2016, Master’s Degree in Chemical Engineering, Polytechnical University of Valencia (Spain), Engineering

2014, Bachelor’s Degree in Chemical Engineering, Polytechnical University of Valencia (Spain), Engineering
  • Experience
(2017-2022) Senior Laboratory Technician, Polytechnical University of Valencia (Spain)
(2020-2022) Teaching of Thermodynamics (2nd year) and Biomaterials (3rd year)

(2019-2020) Teaching of Tissue Engineering (4th year) and Heat Transfer (2nd year)

(2018-2019) Teaching of Thermodynamics (2nd year)
  • Publications/Research achievements
Influence of chemistry and fiber diameter of electrospun PLA, PCL and their blend membranes, intended as cell supports, on their biological behavior.
DOI: 10.1016/j.polymertesting.2021.107364

Role of electrospinning parameters on poly(lactic-co-glycolic acid) and poly(caprolactone-co-glycolic acid) membranes.
DOI: 10.3390/polym13050695

Development of polylactic acid thermoplastic starch formulations using maleinized hemp oil as biobased plasticizer.
DOI: 10.3390/polym13091392

PLA/PCL electrospun membranes of tailored fibres diameter as drug delivery systems.
 DOI: 10.1016/j.eurpolymj.2017.12.045
Scaffolds based on hyaluronan and carbon nanotubes gels.
DOI: 10.1177/0885328216644535
Poster presentation: “Role of the main electrospinning parameters on electrospun membranes based on aliphatic co-polyesters as drug delivery systems.” – ESB2019
Poster presentation: “Characterization of electrospun membranes of P(LA-co-GA) and P(CL-co-GA) membranes". – ESAO2018
Poster presentation: ”Influence of fibre diameter and chemical composition of electrospun polyesters (PLA, PCL and their blend) intended as cell supports on the biological behaviour.” – ESAO2018
Poster presentation: “Assessment of the parameters influencing the fibre characteristics of electrospun P(LA-co-GA) and P(CL-co-GA) membranes,” – ESB2018
Poster presentation: “PLA/PCL electrospun membranes of different fibres diameter as culture supports and delivery of albumin thereof.” – TERMIS2017

Research Project

Dual treatment in skin cancer: a multiscale platform for bioactive compounds delivery

The skin is a crucial organ in the human body as it acts as a barrier against external physical, chemical and biological agents.

When a damage occurs in the skin, which occurs frequently, this function is temporarily lost and that can lead to highly dramatic situations. The most common injuries in skin are wounds, burns and different types of cancer.

This ambitious project involves an innovative and versatile hydrogel as a delivery platform for photothermal and wound healing active ingredients based on a multiscale system composed of nanostructured lipid carriers (NLC) containing natural bioactive compounds (NBC) – such as curcumin –, and gold nanoparticles.

Curcumin requires encapsulation because of its low biodisponibility, high degradation and hydrophobicity. We will use NLC as the main delivery system, however other encapsulation strategies will be explored to obtain different release profiles.

In addition, gold nanoparticles with different shapes (e.g. nanorods, nanospheres) will be integrated in the system to elucidate the best performing geometry for light triggered drug release.

Finally, the biocompatibility, but also biological performance and clinical potential of our formulations will be evaluated and validated, both in vitro then on skin explants from patients and healthy donors, in order to push this project from bench to bedside and pave the way to a true translational research.