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SIF 2nd Cohort Fellows - Maria Herrero Herrero, CY Cergy Paris Université
Curriculum Vitae
- Education
2022, Master’s Degree in Secondary Education, University of Valencia (Spain), Education
2021, University Expert in e-Learning, Polytechnical University of Valencia (Spain), Education
2016, Master’s Degree in Chemical Engineering, Polytechnical University of Valencia (Spain), Engineering
2014, Bachelor’s Degree in Chemical Engineering, Polytechnical University of Valencia (Spain), Engineering
- Experience
(2019-2020) Teaching of Tissue Engineering (4th year) and Heat Transfer (2nd year)
(2018-2019) Teaching of Thermodynamics (2nd year)
- Publications/Research achievements
DOI: 10.1016/j.polymertesting.2021.107364
Role of electrospinning parameters on poly(lactic-co-glycolic acid) and poly(caprolactone-co-glycolic acid) membranes.
DOI: 10.3390/polym13050695
Development of polylactic acid thermoplastic starch formulations using maleinized hemp oil as biobased plasticizer.
DOI: 10.3390/polym13091392
PLA/PCL electrospun membranes of tailored fibres diameter as drug delivery systems.
DOI: 10.1016/j.eurpolymj.2017.12.045
DOI: 10.1177/0885328216644535
https://scholar.google.es/citations?hl=es&user=4uB_LaoAAAAJ
Research Project
Dual treatment in skin cancer: a multiscale platform for bioactive compounds delivery
The skin is a crucial organ in the human body as it acts as a barrier against external physical, chemical and biological agents.
When a damage occurs in the skin, which occurs frequently, this function is temporarily lost and that can lead to highly dramatic situations. The most common injuries in skin are wounds, burns and different types of cancer.
This ambitious project involves an innovative and versatile hydrogel as a delivery platform for photothermal and wound healing active ingredients based on a multiscale system composed of nanostructured lipid carriers (NLC) containing natural bioactive compounds (NBC) – such as curcumin –, and gold nanoparticles.
Curcumin requires encapsulation because of its low biodisponibility, high degradation and hydrophobicity. We will use NLC as the main delivery system, however other encapsulation strategies will be explored to obtain different release profiles.
In addition, gold nanoparticles with different shapes (e.g. nanorods, nanospheres) will be integrated in the system to elucidate the best performing geometry for light triggered drug release.
Finally, the biocompatibility, but also biological performance and clinical potential of our formulations will be evaluated and validated, both in vitro then on skin explants from patients and healthy donors, in order to push this project from bench to bedside and pave the way to a true translational research.
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